Polypeptide products are usually trifluoroacetate. Because of the high biotoxicity of trifluoroacetic acid, this salt type should be avoided in some experiments.
Because of the low biotoxicity of acetic acid, most drug peptides or beauty peptides are acetate. However, the acetate stability of some products is not good, so the sequence stability should be considered.
Less products will choose the hydrochloride. Some sequences require the use of hydrochloride for specific purposes
It will seriously affect the solubility and stability of the product, which needs to be selected according to the sequence.
This usually affects the solubility and stability of the product
Dihydroxynaphthenate is commonly used in the production of peptide drugs as a sustained-release agent
Biotoxicity is relatively low, but due to the complexity of the preparation process, it is necessary to develop the production process separately according to the sequence
Affect the stability of polypeptide products, less used